Postdoctoral Scientist

Profile

Postdoctoral Scientist - Immunology
**MEMBERS ONLY**SIGN UP NOW***.
- NDM Experimental Medicine - Weatherall Institute of Molecular Medicine
Location:
Oxford
Salary:
£33,309 to £40,927 per annum, Grade 7
Hours:
Full Time
Contract Type:
Fixed-Term/Contract
Placed On:
21st March 2022
Closes:
30th March 2022
Job Ref:
156874
NDM Experimental Medicine, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford
THIS IS A RE-ADVERTISEMENT, PREVIOUS APPLICANTS NEED NOT APPLY
We are seeking a Post-doctoral Scientist with strong immunology background to take up a position in Prof Ling-Pei Ho's Translational Lung Immunology group at the MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine. The successful candidate will join a growing programme in immune mechanisms of lung fibrosis and alveolar regeneration in chronic lung fibrosis, with a bridge to testing new immuno-modulatory therapeutic targets in innovative early phase trials. There is also a nascent project on inflammaging in chronic lung fibrosis within the group. There is good link to human samples and established murine programme.
The successful candidate will work on a project to understand immune drivers of fibrotic lung diseases, focusing on idiopathic pulmonary fibrosis (IPF) and fibrotic sarcoidosis. While our work have hitherto focused on monocytes and macrophages, this is now expanding to include all other immune cells, as emergent single cell transcriptomic data in IPF show wider abnormalities in T cells and NK cells. In this project, emphasis will be on functional immunology studies, building new human lung organoids with new 3D bioinstructive materials and inducible progenitors (in collaboration with Hannan/Stevens; Nottingham/Imperial) and relevant transgenic murine studies. The studies will test, define and conclude on hypotheses around how CD4 effector T cells and senescent CD8 T cells might influence lung and bone marrow resident cells in progressing fibrosis. There will be opportunities to use and further develop high end immunological technologies e.g. CYTOF, single cell mass cytometry imaging (Tissue Hyperion) and high resolution cryoEM (in collaboration with Oxford Structural Biology Unit). Large, good quality sets of single cell transcriptomic data from human IPF lungs and longitudinal murine model of resolving lung fibrosis have been generated, and can be mined to support work going forward with dedicated bioinformatics support.
Candidates who have some experience in bioinformatic analysis of transcriptomic data will be particularly desirable.
You will be based in the Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford
The post is fixed term for up to 3 years and is being offered on a full-time basis.
Applications for this vacancy are to be made online. You will be required to upload a supporting statement and CV as part of your online application.
Only applications received before 12:00 midday on 30 March 2022 will be considered.
We value your feedback on the quality of our adverts. If you have a comment to make about the overall quality of this advert, or its categorisation then please send us your feedback
Advert information
Type / Role:
Subject Area(s):
Location(s):
Job tools
PhD Alert Created
Job Alert Created
Your PhD alert has been successfully created for this search.
Your job alert has been successfully created for this search.
Ok
Ok
PhD Alert Created
Job Alert Created
Your PhD alert has been successfully created for this search.
Your job alert has been successfully created for this search.
Manage your job alerts
Manage your job alerts
Account Verification Missing
In order to create multiple job alerts, you must first verify your email address to complete your account creation
Request verification email
Request verification email
jobs.ac.uk Account Required
In order to create multiple alerts, you must create a jobs.ac.uk jobseeker account
Create Account
Create Account
Alert Creation Failed
Unfortunately, your account is currently blocked. Please login to unblock your account.
Login
Login
Email Address Blocked
We received a delivery failure message when attempting to send you an email and therefore your email address has been blocked. You will not receive job alerts until your email address is unblocked. To do so, please choose from one of the two options below.
Re-verify your email
Update your email
Re-verify your email
Update your email
Max Alerts Reached
A maximum of 5 Job Alerts can be created against your account. Please remove an existing alert in order to create this new Job Alert
Manage your job alerts
Manage your job alerts
Creation Failed
Unfortunately, your alert was not created at this time. Please try again.
Ok
Ok
Create PhD Alert
Create Job Alert
When you create this PhD alert we will email you a selection of PhDs matching your criteria.
When you create this job alert we will email you a selection of jobs matching your criteria.
Our Terms and Conditions
and Privacy Policy
apply to this service. Any personal data you provide in setting up this alert is processed in accordance with our Privacy Notice
Create PhD Alert
Create Job Alert
When you create this PhD alert we will email you a selection of PhDs matching your criteria.
When you create this job alert we will email you a selection of jobs matching your criteria.
Our Terms and Conditions
and Privacy Policy
apply to this service. Any personal data you provide in setting up this alert is processed in accordance with our Privacy Notice
I would like to receive email communication from jobs.ac.uk relating to Company News
I would like to receive email communication from jobs.ac.uk relating to Conferences, Meetings and Events
Save this job
Login to Save Job
Max Saved Jobs Reached
×
Max Saved Jobs Reached
A maximum of 500 Saved Jobs can be created against your account. Please remove an existing Saved Job in order to add a new Saved Job.
Manage Saved Jobs
×
Save Job
Please sign in or register for an account to save a job.
Sign In
Register

Company info

Sign Up Now - EducationCrossing.com