Post Doctoral Research Fellow

Profile

Description:
Stronger for longer: towards food supplements that maintain muscle strength with age Based in the Faculty of Health, the School of Biomedical and Healthcare Sciences is committed to three core aims: outstanding clinical education; strong social engagement; and world-class research which all feature strongly in the student learning experience. A key strength is a close relationship with NHS partners, with early clinical contact for all students, who have access to some of the best-resourced laboratories in the UK. Research is organised within the Biomedical Research Group and focuses on understanding the molecular and cellular processes underlying human health and disease, with a key aim to translate this research into diagnostic and therapeutic applications. Investment in state-of-the-art genomic, proteomic and imaging technologies have allowed a systems-led approach to explore the interacting networks of genes, molecules and cells underpinning disease processes. Applications are invited to join the Mitochondrial Biology Labs at the University of Plymouth as a Post-Doctoral Research Assistant to investigate effects of plant-derived peptide hydrolysates on the energy metabolism of human skeletal muscle cells. These investigations are part of an Innovate-UK-funded project that is led by Bell and Loxton Innovations Ltd and that aims to develop a novel circular economy plant protein derivative as a readily digestible ingredient to support healthy ageing. Specifically, we will test the hypothesis that the peptide hydrolysates have bioenergetic effects that mitigate loss of muscle mass and function, i.e., sarcopenia, with age. The global prevalence of sarcopenia is currently estimated 10-27%, and is expected to increase as polulations across the world age. An exciting opportunity to become part of a progressive and cutting-edge UK University near the South West coast as well as Dartmoor National Park, you will perform lab-based research in a commercial and healthcare context, and will thus have the chance to make a real-world difference. Directed by Dr Charles Affourtit, you will develop skills in the functional analysis of cellular bioenergetics and in the quantification of metabolic control and regulation. The team in Plymouth further consists of Prof. Mary Hickson and Drs Jane Carré and Vikram Sharma, who will offer their expertise in dietetics, the cellular basis of muscle atrophy, and proteomics, respectively. You should have a PhD in biochemistry, cellular biology or another relevant area, and a strong interest in the involvement of mitochondria in health and disease. In your supporting statement, please show how you meet the essential criteria outlined in the knowledge, qualifications, training and experience elements of the job description. You are expected to start the lab work on the 1st of December 2023, and will be supported for 12 months in the first instance. For an informal discussion to find out more about the project and role, please contact Charles Affourtit by email via **** or by tele****. Interviews are likely to take place in the week commencing the 16th of October and you will be notified if you have been shortlisted or not. We offer a competitive salary package and a generous pension and holiday scheme. We also offer a range of other benefits, including ongoing development opportunities. The successful candidate may be required to obtain an ATAS Certificate prior to this research being undertaken. Please demonstrate how you meet the essential criteria outlined in the knowledge, qualifications, training and experience elements of the job description in your supporting statement. This is a full-time position working 37 hours per week on a fixed-term basis until 30 November 2024 due to funding. Flexible working options including job share will be considered. The Faculty of Health holds a Silver Athena Swan Award and the University holds a Bronze Athena SWAN Award which recognises commitment to advancing women’s careers in STEMM academia. Staff appointed within the Faculty of Health may be able to join the NHS pension scheme subject to eligibility criteria. The University of Plymouth has a strong interdisciplinary research ethos which is supported by our three strategic Research Institutes; the Marine Institute, the Sustainable Earth Institute, and the Plymouth Institute of Health and Care Research. As a member of our academic community, you’ll be expected to contribute to our recognised research strengths. Working holistically across the University, you will be challenged to innovate, collaborate and deliver impactful research contributions as part of a systems thinking approach to addressing today’s global challenges. The University of Plymouth is a diverse, welcoming community where everyone makes a difference and is encouraged to bring their whole selves to work. To find out more about our inclusive community, initiatives such as Athena Swan and the Race Equality Charter and our range of benefits / support mechanisms such as flexible working, staff networks and enhanced maternity, paternity & adoption leave please visit our Equality, Diversity and Inclusion webpages We particularly welcome applicants from under-represented groups such as BAME/BIPOC and LGBT Job Description
Region:
Location:
Plymouth
Salary:
£38,205 - £44,263 per annum - Grade 7
Package:
Full-Time, Fixed-Term
Contractual hours:
37
Basis:
FT Temporary Fulltime All Year ]]>
Based in the Faculty of Health, the School of Biomedical and Healthcare Sciences is committed to three core aims: outstanding clinical education; strong social engagement; and world-class research which all feature strongly in the student learning experience. A key
strength is a close relationship with NHS partners, with early clinical contact for all students, who have access to some of the best-resourced laboratories in the UK. Research is organised within the Biomedical Research Group and focuses on understanding the molecular and cellular processes underlying human health and disease, with a key aim to translate this research into diagnostic and therapeutic applications. Investment in state-of-the-art genomic, proteomic and imaging technologies have allowed a systems-led approach to explore the interacting networks of genes, molecules and cells underpinning disease processes.
Applications are invited to join the Mitochondrial Biology Labs at the University of Plymouth as a Post-Doctoral Research Assistant to investigate effects of plant-derived peptide hydrolysates on the energy metabolism of human skeletal muscle cells. These investigations are part of an Innovate-UK-funded project that is led by Bell and Loxton Innovations Ltd and that aims to develop a novel circular economy plant protein derivative as a readily digestible ingredient to support healthy ageing. Specifically, we will test the hypothesis that the peptide hydrolysates have bioenergetic effects that mitigate loss of muscle mass and function, i.e., sarcopenia, with age. The global prevalence of sarcopenia is currently estimated 10-27%, and is expected to increase as polulations across the world age.
An exciting opportunity to become part of a progressive and cutting-edge UK University near the South West coast as well as Dartmoor National Park, you will perform lab-based research in a commercial and healthcare context, and will thus have the chance to make a real-world difference. Directed by Dr Charles Affourtit, you will develop skills in the functional analysis of cellular bioenergetics and in the quantification of metabolic control and regulation. The team in Plymouth further consists of Prof. Mary Hickson and Drs Jane Carré and Vikram Sharma, who will offer their expertise in dietetics, the cellular basis of muscle atrophy, and proteomics, respectively.
You should have a PhD in biochemistry, cellular biology or another relevant area, and a strong interest in the involvement of mitochondria in health and disease. In your supporting statement, please show how you meet the essential criteria outlined in the knowledge, qualifications, training and experience elements of the job description. You are expected to start the lab work on the 1st of December 2023, and will be supported for 12 months in the first instance.
For an informal discussion to find out more about the project and role, please contact Charles Affourtit by email via ****
or by tele****.
Interviews are likely to take place in the week commencing the 16th of October and you will be notified if you have been shortlisted or not.
We offer a competitive salary package and a generous pension and holiday scheme. We also offer a range of other benefits, including ongoing development opportunities.
The successful candidate may be required to obtain an ATAS Certificate prior to this research being undertaken.
Please demonstrate how you meet the essential criteria outlined in the knowledge, qualifications, training and experience elements of the job description in your supporting statement.
This is a full-time position working 37 hours per week on a fixed-term basis until 30 November 2024 due to funding.
Flexible working options including job share will be considered.
The Faculty of Health holds a Silver Athena Swan Award and the University holds a Bronze Athena SWAN Award which recognises commitment to advancing women’s careers in STEMM academia.
Staff appointed within the Faculty of Health may be able to join the NHS pension scheme subject to eligibility criteria.
The University of Plymouth has a strong interdisciplinary research ethos which is supported by our three strategic Research Institutes; the Marine Institute, the Sustainable Earth Institute, and the Plymouth Institute of Health and Care Research. As a member of our academic community, you’ll be expected to contribute to our recognised research strengths. Working holistically across the University, you will be challenged to innovate, collaborate and deliver impactful research contributions as part of a systems thinking approach to addressing today’s global challenges.
The University of Plymouth is a diverse, welcoming community where everyone makes a difference and is encouraged to bring their whole selves to work. To find out more about our inclusive community, initiatives such as Athena Swan and the Race Equality Charter and our range of benefits / support mechanisms such as flexible working, staff networks and enhanced maternity, paternity & adoption leave please visit our Equality, Diversity and Inclusion webpages
We particularly welcome applicants from under-represented groups such as BAME/BIPOC and LGBT
Job Description
A9710
£38,205 - £44,263 per annum - Grade 7
38205
38205
44263
Academic/Research
Sun, 1 Oct 2023 00:00:00 GMT
Plymouth
Full-Time, Fixed-Term
37
FT Temporary Fulltime All Year
Tue, 29 Aug 2023 00:00:00 GMT

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