Assistant Professor-FixedTerm

Profile

857449

Work type:

Faculty/Academic Staff

Major Administrative Unit / College:

College Of Human Medicine

Department:

Translational Neuroscience 40000320

Sub Area:

FAS- Fac./Acad Staff

Salary:

Salary Commensurate with Experience

Location:

Grand Rapids

Categories:

Research/Scientific, Fixed Term Faculty, Full Time (90-100%), Non-Union

Working/Functional Title

Ast Prof-Fixed term

Position Summary

The fixed-term assistant professor is expected to lead and participate in multiple avenues of research including the pre-clinical analysis of gene-therapy and neuroregenerative interventions to provide therapeutic benefit and/or reduce common therapeutic side effects in Parkinson’s disease. More specifically investigations will include 1) development of gene level silencing of CaV1.3 channels in brain using rAAV-CaV1.3-sh/miRNA to prevent/reverse the devastating side-effect known as levodopa-induced dyskinesias (LID), decrease motor dysfunction and delay disease progression using parkinsonian animal models, and 2) explore the impact of a common human single nucleotide polymorphism (SNP) on the on the ability to remodel the parkinsonian striatum with new DA terminals using neural grafting in a CRISPR knock-in rat model of the human SNP rs6265 BDNF as a model system. This person also is expected to develop their own independent areas of research that will compliment/expand translational research efforts in the Translational Neuroscience unit in the College of Human Medicine at MSU. The candidate will be expected to participate in mentoring and instruction of students in MSU graduate training programs and work with existing faculty to broaden and enhance the vision for research at MSU.

Equal Employment Opportunity Statement

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, citizenship, age, disability or protected veteran status.

Required Degree

Doctorate -Parkinson's disease, translational neuro

Minimum Requirements

The position requires a PhD or equivalent with a record of scholarship and grant awards in Parkinson’s disease research commensurate with experience. An established track record of participating in multidisciplinary team-based collaborations is essential as well as experience mentoring students/fellows.

Desired Qualifications

Five or more years experience in cell, molecular, and histological techniques such as cell culture, flow cytometry, RNA in situ hybridization, q/ddPCR, western blot, ELISA, immunohistochemistry, and confocal microscopy are desired. Applicants with proficiency in performing stereotaxic surgeries, animal husbandry and behavior studies, as well as post-mortem tissue processing are strongly encouraged to apply.

Required Application Materials

1) Cover Letter

2) Current Curriculum Vitae with contact information

3) List of three references with contact information

Special Instructions

n/a

Review of Applications Begins On

05/02/2023

Summary of Health Risks

Work with animals or unfixed animal tissue.

Website

https://translationalscience.msu.edu/

Department Statement

The nationally ranked Department of Translational Neuroscience within CHM focuses on neurodegenerative diseases of aging including Parkinson’s disease, Alzheimer’s disease, allied dementias and traumatic brain injury. Translational Neuroscience is headquartered in the Grand Rapids Innovation Park within the state-of-the-art Grand Rapids Research Center (GRRC). The over $200 million expansion of CHM in Grand Rapids is a coordinated effort among local partner medical systems (Spectrum Health, Mercy Health Saint Mary’s) and research-intensive institutions (CHM, Van Andel Research Institute) to bring basic researchers and clinicians together to create unified translational science initiatives. With these resources, CHM and its partner institutions in Grand Rapids have laid the foundation to create a regional geographic nexus unparalleled in its commitment to neuroscience research excellence.

MSU Statement

Michigan State University has been advancing the common good with uncommon will for more than 160 years. One of the top research universities in the world, MSU pushes the boundaries of discovery and forges enduring partnerships to solve the most pressing global challenges while providing life-changing opportunities to a diverse and inclusive academic community through more than 200 programs of study in 17 degree-granting colleges.

Advertised:

Apr 24, 2023

Eastern Daylight Time

Applications close:

Apr 24, 2025

Eastern Daylight Time

Company info

Michigan State University
Website : http://www.msu.edu